Are you interested in measuring Resting Metabolic Rate and nutrient oxidation in humans? Do you want to find out how the performance of metabolic carts can be tested, and how a most optimal system can be chosen? Then this book is an essential reading for you. Contact us to receive a free hardcopy, as long as supplies last. Background of this doctoral thesis: Indirect calorimetry (IC) is the reference method to assess human resting metabolic rate (RMR), the largest component of total energy expenditure, except in extremely active individuals. In addition to RMR, IC also allows to determine the respiratory exchange ratio (RER), which gives valuable information about the type of energy substrates (fat vs. carbohydrate) being metabolized. Among the available IC systems, metabolic carts are the most extended in both research and clinical settings. The Deltatrac metabolic cart (Datex Instrumentarium Corp, Helsinki, Finland), which has been for long considered the gold standard for assessing RMR, is no longer manufactured. Numerous research groups around the world are deeply studying human RMR and RER and its regulation. Therefore, the identification of valid metabolic carts and data analysis methodology is of great importance. On the other hand, the method for IC data analysis commonly differs across studies, and the use of different methods might result in different estimates of RMR and RER.